Everton captain Phil Neville will be missing for 6-8 weeks, while Blackburn Rovers have a fully fit squad to pick from.
Striker Benni McCarthy has overcome an ankle injury but is unlikely to supplant Jason Roberts or El Hadj Diouf in the starting line-up.
Also returning for Sam Allardyce's side is midfielder Steven Nzonzi, who has recovered from a foot injury.
Defender Lars Jacobsen may face his old club, Everton, but veteran centre back Michel Salgado is also pushing for a starting position.
Everton manager David Moyes may push Johnny Heitinga into a defensive midfield position to cover for the absence of Phil Neville, with Tony Hibbert partnering Joseph Yobo at centre back.
Facing a late fitness test is winger?Diniyar Bilyaletdinov, who has a groin strain.
New signing Lucas Neill joined too late to play any part in this match.
KICK-OFF: SUNDAY SEPTEMBER 20th 15:00 GMT
EVERTON vs BLACKBURN ODDS AND MATCH BETTING
Everton to win: 5/6 at Boylesports - Click to bet or open account
Blackburn to win: 4/1 at Bet365 - Click to bet or open account
Draw: 5/2 at Stan James - Click to bet or open account
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