Manuel Almunia is set to return to goalkeeping duties for Arsenal, while Tottenham manager Harry Redknapp may hand a start to David Bentley.
Bentley looked sharp in Spurs' midweek Carling Cup match and with winger Aaron Lennon doubtful with an ankle problem, Bentley is the most likely replacement.
Elsewhere, Peter Crouch will again partner Robbie Keane in attack in the absence of the suspended Jermaine Defoe, while Ledley King and Sebastien Bassong look the most likely central defensive pairing.
Fellow defender Jonathan Woodgate is not likely to be risked after his head injury last time out.
Arsenal boss Arsene Wenger will recall Cesc Fabregas, Andriy Arshavin and Robin Van Persie after the three players were rested for the Carling Cup.
Eduardo and Nicklas Bendtner are set for places on the bench, alongside the fit again Samir Nasri, who has recovered from a broken leg.
Theo Walcott and Denilson are still sidelined with injury.
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Post from: Premiership Today Football News
