Salomon Kalou is rated doubtful for Carlo Ancelotti's Chelsea, while home side Bolton Wanderers are set to bring back Kevin Davies after the striker was rested for the midweek Carling Cup match.
Davies will return to lead the line while the fit again Johan Elmander will be on the bench, alongside Ivan Klasnic, who scored the winner in Bolton's 3-2 victory over Everton last time out.
With Tamir Cohen and Lee Chung-Yong impressing so far, Bolton boss Gary Megson is set to stick with the same starting eleven as in Bolton's previous home game.
With Ashley Cole (ankle), Jose Bosingwa (knee), Yuri Zhirkov (knee) and John Mikel Obi (knee) all out and Salomon Kalou and Branislav Ivanovic doubts; Chelsea boss Carlo Ancelotti is set to name a few changes to his starting line-up.
Juliano Belletti and Paulo Ferreira will start at full back, with Petr Cech returning to goal, having been rested in midweek.
Joe Cole may get another start at the expense of Deco after impressing in recent games with Didier Drogba and Nicolas Anelka the preferred forward partnership.
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